DNA origami nanotechnology for microRNA detection
A revolutionary blood test for breast cancer early detection
MicroRNAs (miRNAs) small RNA molecules recognized as valuable blood-based
biomarkers for cancer detection and monitoring. Their clinical importance was underscored by the awarding of the 2024 Nobel Prize in Physiology or Medicine.
Current miRNA detection technologies are costly, complex, and require specialized laboratories — limiting their accessibility in both clinical and research settings.
To overcome these challenges, we have developed an innovative DNA origami nanosensor technology that enables rapid, highly sensitive, and specific detection of miRNAs in serum and plasma, with minimal sample preparation.
Target miRNA detection is indicated by a fluorescence signal, and the technology is easily adaptable for multiplexing — enabling simultaneous detection of multiple miRNAs.
Our initial focus is on developing this platform for Research Use Only (RUO) applications in oncology, cardiovascular, immuno-inflammatory, and neurodegenerative diseases, offering a rapid and cost-effective alternative to PCR and sequencing. Clinical applications will follow.
Our technology is intellectually protected
For more information download our brochure HERE
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